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Anxiogenic behaviour induced by 17α-ethynylestradiol in male guppies (Poecilia reticulata)
Södertörn University, School of Life Sciences, Environmental science. Södertörn University, School of Life Sciences, Biology.
Södertörn University, School of Life Sciences, Environmental science.
Södertörn University, School of Life Sciences, Environmental science.
Södertörn University, School of Life Sciences, Environmental science. Södertörn University, School of Life Sciences, Biology.
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2011 (English)In: Fish Physiology & Biochemistry, ISSN 0920-1742, E-ISSN 1573-5168, Vol. 37, no 4, p. 911-918Article in journal (Refereed) Published
Abstract [en]

Behaviour studies are used in toxicology research as they are excellent tools to measure physiological end-points caused by exogenous chemicals. In mammals both reproductive and non-reproductive behaviours have been used for a long period of time, whereas in teleost fishes non-reproductive behaviours have received little attention compared to reproductive behaviours. Recent advances in measuring stress related behaviours in zebrafish have provided additional tools to understand behaviour toxicology in fish. One species with well documented reproductive behaviour disturbed by different toxicants is the guppy, which is better suited than zebrafish for reproductive behaviour studies and therefore might be a better model organism for comparative behaviour studies in fish toxicology. Here we report new applications for non-reproductive behaviours in guppy and test these behaviours on males treated with the endocrine disruptor 17α-ethynylestradiol at environmentally relevant concentrations. 17α-ethynylestradiol increased freezing and bottom-dwelling when fish were placed in a non-familiar aquarium, but did not significantly affect shoaling behaviour. These results are similar to the anxiogenic behaviours seen in rats treated perinatally with 17α-ethynylestradiol and add more concern to the impacts of endocrine disruptors on aquatic wildlife.

Place, publisher, year, edition, pages
2011. Vol. 37, no 4, p. 911-918
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Biological Sciences
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URN: urn:nbn:se:sh:diva-8616DOI: 10.1007/s10695-011-9488-xISI: 000296646800018PubMedID: 21537944Scopus ID: 2-s2.0-80355132249OAI: oai:DiVA.org:sh-8616DiVA, id: diva2:417624
Available from: 2011-05-17 Created: 2011-05-17 Last updated: 2017-12-11Bibliographically approved

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Hallgren, StefanVolkova, KristinaReyhanian, NasimOlsén, K HåkanPorsch Hällström, Inger

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