The purpose of this essay is to describe what difficulties and challenges are for teachers of religious education at upper secondary school. The essay is written from a teacher's perspective, where the focus is on the teacher's perceptions of the difficulties and challenges of teaching religious education. The methodology for the collection of information was done through qualitative interviews. Previous research shows that one of the challenges in the teaching profession is the interpretation of the curriculum, and then which of those is correct. The essay shows that the biggest challenges that teachers experience in the subject of religious education is the students' prejudice against different religious groups, and also the difficulty of getting students to understand the purpose of what is being taught. I have examined how teachers handle these difficulties and challenges as well as the didactic choices that are at the forefront of the teachers' strategies.