This thesis is an analysis of how international policies on HIV prevention can be understood through a postcolonial perspective and how these prevention strategies are reflected nationally and locally in Babati, Tanzania. To gain knowledge of these aims I have focused on UNAIDS and the US’ government policies to get an idea of where the international discourse about HIV prevention stands. My empirical data in Babati is collected by semi-structural interviews with people who work with HIV prevention. I have used Chandra Talpade Mohanty’s understanding of Third World women, together with Jenny Kitzinger theory about women in HIV discourses and Karen M Booth’s view of how international policies are trying to empower women to reduce their risk of HIV infection. To assist my analysis I have focused on three notions, which are recurring in the HIV prevention discourse, these are: empowerment of women, condom use and sexual behaviour. These notions help to establish the HIV discourse and later I have compared the results with my theoretical framework and empirical findings. My final conclusion is that international policies on HIV prevention can be seen as imperialistic as they are promoting a certain change in sexual behaviour, such as reduction of partners and abstinence until marriage.