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'Arc' escorts siRNAs in heterochromatin assembly
Södertörn University, School of Life Sciences. Karolinska Institute.
2007 (English)In: Nature Structural & Molecular Biology, ISSN 1545-9993, E-ISSN 1545-9985, Vol. 14, no 3, 178-179 p.Article in journal, Editorial material (Other academic) Published
Abstract [en]

RNA interference (RNAi) is important in directing heterochromatin assembly at centromeres in fission yeast, which is crucial for maintaining a stable genome through mitotic and meiotic divisions. In this issue, Buker et al. describe a new Argonaute siRNA chaperone (ARC) that converts duplex RNA to single-stranded RNA. This is a previously unknown step in the RNAi-directed heterochromatin-formation pathway.

Place, publisher, year, edition, pages
2007. Vol. 14, no 3, 178-179 p.
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Biochemistry and Molecular Biology
URN: urn:nbn:se:sh:diva-22601DOI: 10.1038/nsmb0307-178ISI: 000244715200004PubMedID: 17334405ScopusID: 2-s2.0-33847616942OAI: diva2:700094
Available from: 2014-03-03 Created: 2014-03-03 Last updated: 2014-03-03Bibliographically approved

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