Oxygenation of 2,3-dihydroindoles
2002 (English)In: Tetrahedron, ISSN 0040-4020, E-ISSN 1464-5416, Vol. 58, no 45, 9187-9191 p.Article in journal (Refereed) Published
Isatogens (3-oxo-3H-indole 1-oxides) possess interesting biological properties and development of a general method to construct these derivatives has now been developed. Indolines (2,3-dihydroindoles) and isatogens have been prepared in an efficient route starting from indoles substituted in position 2. Reduction of the 2-substituted indoles was performed with tin and hydrochloric acid to give racemic indolines, which were converted to isatogens by 3-chloroperoxybenzoic acid (m-CPBA).
Place, publisher, year, edition, pages
2002. Vol. 58, no 45, 9187-9191 p.
IdentifiersURN: urn:nbn:se:sh:diva-15774DOI: 10.1016/S0040-4020(02)01198-5ISI: 000179069000005ScopusID: 2-s2.0-0037020798OAI: oai:DiVA.org:sh-15774DiVA: diva2:508480