Detection strategies of tick-borne encephalitis virus in Swedish Ixodes ricinus reveal evolutionary characteristics of emerging tick-borne flaviviruses.
2007 (English)In: Archives of Virology, ISSN 0304-8608, E-ISSN 1432-8798, Vol. 152, no 5, 1027-1034 p.Article in journal (Refereed) Published
The flaviviral tick-borne encephalitis virus (TBEV) is a human pathogen having significant impact on public health. The geographical distribution of TBEV and TBEV-like viruses is increasing, which makes it important to characterise the natural virus populations. Here we present four RT-PCR strategies designed for detection of broad types of tick-borne flaviviruses. Sequence information on more than 32% of a TBEV genome was generated from a small pool of ticks collected in the Stockholm archipelago on the island of Torö. The sequences were characterised and compared with those of other tick-borne flaviviruses, which classified the virus as Western European TBEV.
Place, publisher, year, edition, pages
2007. Vol. 152, no 5, 1027-1034 p.
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:sh:diva-6063DOI: 10.1007/s00705-006-0922-9ISI: 000245965300018PubMedID: 17277902ScopusID: 2-s2.0-34247481383OAI: oai:DiVA.org:sh-6063DiVA: diva2:395524