sh.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • harvard-anglia-ruskin-university
  • apa-old-doi-prefix.csl
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
The association between vitamin D deficiency and tuberculosis: Effects of different levels of vitamin D deficiency - A meta-analysis
Södertörn University, School of Natural Sciences, Technology and Environmental Studies.
2019 (English)Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
Abstract [en]

Aim: To conduct a systematic review and meta-analysis of all published studies studying the risk of vitamin D deficiency in tuberculosis patients and in healthy controls. Additionally, subgroup meta-analysis was performed based on the level of vitamin D to test the risk in TB groups and in healthy groups.

Methods: Pubmed was searched for observational studies in human and English that discussed the association between risk of low serum vitamin D and TB. Meta-analysis was performed on all relevant studies combined and for subgroups of each vitamin D level.

Results: 22 studies were selected and pooled in the analysis. The results were consistent with previous studies examining the same risk. The overall log risk ratio (log RR) of low vitamin D was significantly higher in TB patients 1.68 times than healthy controls. In 4 subgroup meta- analyses based on vitamin D level below (20 nmol/L, 30 nmol/L, 50 nmol/L, and 75 nmol/L), the risk of having low vitamin D in TB patients was (1.82, 2.89, 1.38, 1.32) respectively. That subgroup analysis showed more clearly the higher RR were below 20 and 30 nmol/L. The smallest RR was at 75 nmol/L level.

Conclusion: This study verified the association between risk of low vitamin D level and TB development. It also clarified that, the risk increased by decreasing vitamin D level.

Place, publisher, year, edition, pages
2019. , p. 39
National Category
Natural Sciences Biological Sciences Infectious Medicine
Identifiers
URN: urn:nbn:se:sh:diva-38922OAI: oai:DiVA.org:sh-38922DiVA, id: diva2:1349227
Subject / course
Environmental Science
Uppsok
Life Earth Science
Supervisors
Available from: 2019-09-26 Created: 2019-09-07 Last updated: 2019-09-26Bibliographically approved

Open Access in DiVA

fulltext(946 kB)15 downloads
File information
File name FULLTEXT02.pdfFile size 946 kBChecksum SHA-512
0825b24df25faa825194e3f392b7dd7a4ecf3dbf03284d14c34a181712429b6225e99ab502c14c3c37f35727a060cc32f813c11d92088589fc64c6c0c7b1a9b3
Type fulltextMimetype application/pdf

By organisation
School of Natural Sciences, Technology and Environmental Studies
Natural SciencesBiological SciencesInfectious Medicine

Search outside of DiVA

GoogleGoogle Scholar
Total: 19 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

urn-nbn

Altmetric score

urn-nbn
Total: 78 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • harvard-anglia-ruskin-university
  • apa-old-doi-prefix.csl
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf