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A communal catalogue reveals Earth’s multiscale microbial diversity
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Antal upphovsmän: 3032017 (Engelska)Ingår i: Nature, ISSN 0028-0836, E-ISSN 1476-4687, Vol. 551, s. 457-463Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Our growing awareness of the microbial world's importance and diversity contrasts starkly with our limited understanding of its fundamental structure. Despite recent advances in DNA sequencing, a lack of standardized protocols and common analytical frameworks impedes comparisons among studies, hindering the development of global inferences about microbial life on Earth. Here we present a meta-analysis of microbial community samples collected by hundreds of researchers for the Earth Microbiome Project. Coordinated protocols and new analytical methods, particularly the use of exact sequences instead of clustered operational taxonomic units, enable bacterial and archaeal ribosomal RNA gene sequences to be followed across multiple studies and allow us to explore patterns of diversity at an unprecedented scale. The result is both a reference database giving global context to DNA sequence data and a framework for incorporating data from future studies, fostering increasingly complete characterization of Earth's microbial diversity.

Ort, förlag, år, upplaga, sidor
2017. Vol. 551, s. 457-463
Nationell ämneskategori
Miljövetenskap
Forskningsämne
Miljövetenskapliga studier
Identifikatorer
URN: urn:nbn:se:sh:diva-33742DOI: 10.1038/nature24621ISI: 000416043700036Scopus ID: 2-s2.0-85034804875OAI: oai:DiVA.org:sh-33742DiVA, id: diva2:1160862
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The Earth Microbiome Project Consortium includes principal investigators and scientists who were involved with the individual studies that make up the EMP. These individuals conceived of sampling regimes, collected samples, provided sample metadata, and published manuscripts about individual studies 

Tillgänglig från: 2017-11-28 Skapad: 2017-11-28 Senast uppdaterad: 2018-04-05Bibliografiskt granskad

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