Using a gendered crisis approach, this study investigates the impact of sanctions on Iranian women's nascent entrepreneurial behaviours. Using data from the Global Entrepreneurship Monitor's individual-level data and sanctions intensity data on 10,781 individuals, aged 18-65 from 2008 to 2018, the findings indicate that sanctions lower the perceived opportunities to start a business for women more so than for men. Although sanctions did not influence perceived start-up skills, suggesting resilience among women amid the challenges, sanctions did reduce the fear of failure for women more so than for men. Policymakers, both in the Collective West and in Iran, can use these insights to develop gender-inclusive measures and support women's entrepreneurship in sanction-affected contexts.