In today's changing world, the manufacturing industry faces challenges with digital transformation. The application of new, developed IT-support is used to change business processes and is a central part of today's business development. Digitization has an extensive role and is used to streamline, optimize, and increase productivity in manufacturing. Today, data and analysis can be used to make fact-based decisions where measurement data from manufacturing units can be visualized in real time. Digitization therefore needs to be handled by all industries, not least for the process industry, which has fallen behind in the digital era. Changing business processes in production units using digital strategies can generate increased profitability and productivity. On the other hand, applying IT support requires that businesses need to organize and structure the changes in line with the business processes and manage the information flows that are continuously generated. The study has been carried out with a qualitative research strategy and as a case. The studied case consists of a company within the Swedish process industry that operates globally. The study's empiricism is based on 11 semi-structured interviews on the strategic, tactical, and operational level of the business and the respondents were selected with a snowball sample. The result identifies factors that are considered important for the implementation of changes in an IT-reliant work system. The factors identified are competence provision, communication, participation and the participants' motivation and commitment. Thus, the study has found some aspects where businesses need to consider this at a strategic, tactical, and operational level.