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Publications (10 of 18) Show all publications
Koyanagi, A., Lara, E., Stubbs, B., Carvalho, A. F., Oh, H., Stickley, A., . . . Vancampfort, D. (2018). Chronic Physical Conditions, Multimorbidity, and Mild Cognitive Impairment in Low- and Middle-Income Countries. Journal of The American Geriatrics Society.
Open this publication in new window or tab >>Chronic Physical Conditions, Multimorbidity, and Mild Cognitive Impairment in Low- and Middle-Income Countries
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2018 (English)In: Journal of The American Geriatrics Society, ISSN 0002-8614, E-ISSN 1532-5415Article in journal (Refereed) Epub ahead of print
Abstract [en]

OBJECTIVES: To assess the association between chronic physical conditions and multimorbidity and mild cognitive impairment (MCI) in low- and middle-income countries (LMICs).

DESIGN: Nationally representative, cross-sectional, community-based study.

SETTING: Six countries that participated in the World Health Organization Study on Global Ageing and Adult Health.

PARTICIPANTS: Individuals aged 50 and older (N=32,715; mean age 62.1 ± 15.6; 51.7% female).

MEASUREMENTS: The definition of MCI was based on the recommendations of the National Institute on Ageing and Alzheimer's Association. Ten chronic conditions were assessed (angina pectoris, arthritis, asthma, cataract, chronic lung disease, diabetes mellitus, edentulism, hearing problems, hypertension, stroke). Multivariable logistic regression analysis was conducted to assess the association between chronic physical conditions, multimorbidity (≥2 chronic conditions), and MCI.

RESULTS: The prevalence of multimorbidity was 49.8% (95% confidence interval (CI)=48.1-51.5%) and of MCI was 15.3% (95% CI=14.4-16.3%). After adjustment for potential confounders, edentulism (odds ratio (OR)=1.24), arthritis (OR=1.24), chronic lung disease (OR=1.29), cataract (OR=1.33), stroke (OR=1.94), hearing problems (OR=2.27), and multimorbidity (OR=1.40) were significantly associated with MCI. There was a gradual increase in the likelihood of MCI (1 condition: OR=1.21, 95% CI=1.03-1.42; ≥4 conditions: OR=2.07, 95% CI=1.70-2.52).

CONCLUSION: These results highlight the need to investigate the underlying mechanisms linking chronic conditions and MCI and whether prevention or treatment of chronic conditions or multimorbidity can reduce the onset of cognitive decline and subsequent dementia, especially in LMICs.

Keyword
chronic physical conditions, low- and middle-income countries, mild cognitive impairment, multimorbidity
National Category
Sociology
Identifiers
urn:nbn:se:sh:diva-34620 (URN)10.1111/jgs.15288 (DOI)29427504 (PubMedID)
Available from: 2018-02-15 Created: 2018-02-15 Last updated: 2018-02-15Bibliographically approved
Stickley, A. & Koyanagi, A. (2018). Physical multimorbidity and loneliness: A population-based study. PLoS ONE, 13(1), Article ID e0191651.
Open this publication in new window or tab >>Physical multimorbidity and loneliness: A population-based study
2018 (English)In: PLoS ONE, ISSN 1932-6203, E-ISSN 1932-6203, Vol. 13, no 1, article id e0191651Article in journal (Refereed) Published
Abstract [en]

Multimorbidity has been linked to a variety of negative outcomes although as yet, there has been little research on its association with loneliness. This study examined the association between physical multimorbidity (≥ 2 physical diseases) and loneliness in the general population and its potential mediators. Data came from the Adult Psychiatric Morbidity Survey 2007 (N = 7403, aged ≥16 years). Information was obtained on 20 doctor diagnosed physical conditions that were present in the previous year. An item from the Social Functioning Questionnaire (SFQ) was used to obtain information on loneliness. Multivariable logistic regression analysis was used to examine associations. An increasing number of physical diseases was associated with higher odds for loneliness. Compared to no physical diseases, the odds ratio (OR) (95% confidence interval: CI) for loneliness increased from 1.34 (1.13-1.59) to 2.82 (2.11-3.78) between one and ≥5 physical diseases. This association was particularly strong in the youngest age group (i.e. 16-44 years). The loneliness-physical multimorbidity association was significantly mediated by stressful life events (% mediated 11.1%-30.5%), anxiety (30.2%), and depression (15.4%). Physical multimorbidity is associated with increased odds for loneliness. Prospective research is now needed to further elucidate this association and the factors that underlie it.

National Category
Sociology
Identifiers
urn:nbn:se:sh:diva-34492 (URN)10.1371/journal.pone.0191651 (DOI)000423412500065 ()29364978 (PubMedID)2-s2.0-85041125808 (Scopus ID)
Available from: 2018-02-02 Created: 2018-02-02 Last updated: 2018-02-16Bibliographically approved
Stickley, A., Koyanagi, A., Takahashi, H., Ruchkin, V., Inoue, Y. & Kamio, Y. (2017). Attention-deficit/hyperactivity disorder and physical multimorbidity: A population-based study. European psychiatry, 45, 227-234.
Open this publication in new window or tab >>Attention-deficit/hyperactivity disorder and physical multimorbidity: A population-based study
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2017 (English)In: European psychiatry, ISSN 0924-9338, E-ISSN 1778-3585, Vol. 45, p. 227-234Article in journal (Refereed) Published
Keyword
ADHD, Multimorbidity, Physical disease, Epidemiology, Stress
National Category
Psychiatry
Identifiers
urn:nbn:se:sh:diva-33148 (URN)10.1016/j.eurpsy.2017.07.010 (DOI)000414461300032 ()28957792 (PubMedID)2-s2.0-85029816109 (Scopus ID)
Available from: 2017-08-22 Created: 2017-08-22 Last updated: 2017-11-24Bibliographically approved
Ruchkin, V., Koposov, R. A., Koyanagi, A. & Stickley, A. (2017). Suicidal Behavior in Juvenile Delinquents: The Role of ADHD and Other Comorbid Psychiatric Disorders. Child Psychiatry and Human Development, 48(5), 691-698.
Open this publication in new window or tab >>Suicidal Behavior in Juvenile Delinquents: The Role of ADHD and Other Comorbid Psychiatric Disorders
2017 (English)In: Child Psychiatry and Human Development, ISSN 0009-398X, E-ISSN 1573-3327, Vol. 48, no 5, p. 691-698Article in journal (Refereed) Published
Abstract [en]

This study evaluated the role of psychiatric morbidity in relation to a history of suicidal behavior, with a particular focus on attention-deficit/hyperactivity disorder (ADHD). Suicidality and psychiatric diagnoses were assessed in 370 incarcerated male juvenile delinquents from Northern Russia using the semi-structured K-SADS-PL psychiatric interview. A lifetime history of suicidal ideation only (24.7 %) and suicidal ideation with suicide attempts (15.7 %) was common. Binary logistic regression analysis was used to assess the role of ADHD and other psychiatric disorders in suicidal ideation and suicide attempts. A history of suicidal ideation and of suicide attempts were associated with higher rates of psychiatric morbidity and with the number of comorbid psychiatric disorders. An ADHD diagnosis was associated with an increased risk for both suicidal ideation and for suicide attempts. The comorbidity of ADHD with drug dependence further increased the risk for suicidal ideation, while ADHD and alcohol dependence comorbidity increased the risk for suicide attempts. Our findings highlight the importance of adequately detecting and treating psychiatric disorders in vulnerable youths, especially when they are comorbid with ADHD.

Keyword
ADHD, Juvenile delinquents, Psychopathology, Suicide
National Category
Sociology
Identifiers
urn:nbn:se:sh:diva-31075 (URN)10.1007/s10578-016-0693-9 (DOI)000412534900001 ()27734259 (PubMedID)
Available from: 2016-11-03 Created: 2016-11-03 Last updated: 2017-10-27Bibliographically approved
DeVylder, J. E., Koyanagi, A., Unick, J., Oh, H., Nam, B. & Stickley, A. (2016). Stress Sensitivity and Psychotic Experiences in 39 Low- and Middle-Income Countries. Schizophrenia Bulletin, 42(6), 1353-1362.
Open this publication in new window or tab >>Stress Sensitivity and Psychotic Experiences in 39 Low- and Middle-Income Countries
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2016 (English)In: Schizophrenia Bulletin, ISSN 0586-7614, E-ISSN 1745-1701, Vol. 42, no 6, p. 1353-1362Article in journal (Refereed) Published
Abstract [en]

Stress has a central role in most theories of psychosis etiology, but the relation between stress and psychosis has rarely been examined in large population-level data sets, particularly in low- and middle-income countries. We used data from 39 countries in the World Health Survey (n = 176 934) to test the hypothesis that stress sensitivity would be associated with psychotic experiences, using logistic regression analyses. Respondents in low-income countries reported higher stress sensitivity (P < .001) and prevalence of psychotic experiences (P < .001), compared to individuals in middle-income countries. Greater stress sensitivity was associated with increased odds for psychotic experiences, even when adjusted for co-occurring anxiety and depressive symptoms: adjusted odds ratio (95% CI) = 1.17 (1.15-1.19) per unit increase in stress sensitivity (range 2-10). This association was consistent and significant across nearly every country studied, and translated into a difference in psychotic experience prevalence ranging from 6.4% among those with the lowest levels of stress sensitivity up to 22.2% among those with the highest levels. These findings highlight the generalizability of the association between psychosis and stress sensitivity in the largest and most globally representative community-level sample to date, and support the targeting of stress sensitivity as a potential component of individual- and population-level interventions for psychosis.

National Category
Sociology
Identifiers
urn:nbn:se:sh:diva-29942 (URN)10.1093/schbul/sbw044 (DOI)000388029100011 ()27109925 (PubMedID)2-s2.0-84994430037 (Scopus ID)
Available from: 2016-05-02 Created: 2016-05-02 Last updated: 2017-06-30Bibliographically approved
Stickley, A., Koyanagi, A., Koposov, R., McKee, M., Murphy, A. & Ruchkin, V. (2015). Binge drinking and eating problems in Russian adolescents. Alcoholism: Clinical and Experimental Research, 39(3), 540-547.
Open this publication in new window or tab >>Binge drinking and eating problems in Russian adolescents
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2015 (English)In: Alcoholism: Clinical and Experimental Research, ISSN 0145-6008, E-ISSN 1530-0277, Vol. 39, no 3, p. 540-547Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Binge drinking may be linked to problematic eating behavior, although as yet, little research has been conducted on this association. The objective of this study was to examine the relationship between binge drinking and eating problems in Russian adolescents.

METHODS: Data were drawn from the Social and Health Assessment, a cross-sectional school-based survey of 6th to 10th grade students (aged 12 to 17 years old) carried out in Arkhangelsk, Russia. Information was collected on various eating problems (worries about weight, feeling fat, excessive eating, fasting and excessive exercise, and purging behaviors) and binge drinking (5 or more drinks in a row). Logistic regression analysis was used to examine the relationship between binge drinking and eating problems.

RESULTS: Among the 2,488 adolescents included in the statistical analysis, nearly 50% of girls expressed worries about their weight, while 35.0 and 41.5% of adolescent boys and girls reported excessive eating, respectively. The prevalence of purging behaviors (vomiting/using laxatives) was, however, much lower among both sexes (females-2.6%; males-3.3%). In a regression model adjusted for demographic factors and depressive symptoms, among girls, binge drinking was associated with 5 of the 6 eating problems with odds ratios (ORs) ranging from 1.21 (upset about weight gain) to 1.68 (excessive eating). For boys, binge drinking was linked to feeling overweight (OR: 1.47, confidence interval [CI]: 1.20 to 1.81) and vomiting/used laxatives (OR: 4.13, CI: 1.58 to 10.80).

CONCLUSIONS: Many adolescents in Russia report problematic eating attitudes and behaviors, and eating problems are associated with binge drinking. More research is now needed in this setting to better understand adolescent eating problems and their association with alcohol misuse, so that contextually suitable interventions can be implemented to reduce these behaviors and mitigate their potentially detrimental effects.

National Category
Sociology
Research subject
Baltic and East European studies
Identifiers
urn:nbn:se:sh:diva-26533 (URN)10.1111/acer.12644 (DOI)000350641000019 ()25703623 (PubMedID)2-s2.0-84923789104 (Scopus ID)
Available from: 2015-03-05 Created: 2015-03-05 Last updated: 2017-06-19Bibliographically approved
Stickley, A., Koyanagi, A. & Kawakami, N. (2015). Childhood adversities and adult-onset chronic pain: Results from the World Mental Health Survey, Japan. European Journal of Pain, 19(10), 1418-1427.
Open this publication in new window or tab >>Childhood adversities and adult-onset chronic pain: Results from the World Mental Health Survey, Japan
2015 (English)In: European Journal of Pain, ISSN 1090-3801, E-ISSN 1532-2149, Vol. 19, no 10, p. 1418-1427Article in journal (Refereed) Published
Abstract [en]

Background: Childhood adversities (CAs) have been associated with adult-onset chronic pain. However, to date, most single country studies on this association have been undertaken in Western countries. This study examined the association in Japan where information is scarce. Methods: Data were drawn from the World Mental Health Survey Japan, a population-based cross-sectional survey undertaken in 11 areas of Japan in 2002-2006. We analyzed data from adults aged ≥20 years who provided information on CAs occurring before age 18 years and chronic pain (n = 1740). Cox proportional hazard models were used to estimate the risk for different forms of adult-onset chronic pain (arthritis/rheumatism, neck/back pain, headache and any pain) as a function of the presence of 11 different types of CA and the number of CAs. Results: In the adjusted models, significant associations were observed between: physical abuse and neck/back pain (HR 2.55) and any pain (HR 1.88); sexual abuse and any pain (HR 2.84). Significant dose-dependent relationships were also observed between a greater number of CAs and some adult-onset chronic pain conditions (neck/back and any pain). Conclusions: The results of this study suggest that in Japan, some forms of CA may be associated with certain types of adult-onset chronic pain, in particular neck/back pain. © 2015 European Pain Federation - EFIC®.

National Category
Sociology
Identifiers
urn:nbn:se:sh:diva-26926 (URN)10.1002/ejp.672 (DOI)000362691400004 ()25736867 (PubMedID)2-s2.0-84943658849 (Scopus ID)
Available from: 2015-04-20 Created: 2015-04-20 Last updated: 2017-07-03Bibliographically approved
Kravchenko, Z., Stickley, A. & Koyanagi, A. (2015). Close Relationships Matter: Family Well-being and its Effects on Health in Russia. Europe-Asia Studies, 67(10), 1635-1655.
Open this publication in new window or tab >>Close Relationships Matter: Family Well-being and its Effects on Health in Russia
2015 (English)In: Europe-Asia Studies, ISSN 0966-8136, E-ISSN 1465-3427, Vol. 67, no 10, p. 1635-1655Article in journal (Refereed) Published
Abstract [en]

Dramatic fluctuations have occurred in population health in Russia since the collapse of the Soviet Union. Although many factors have been examined in connection with this, there has been little focus on the role of the family, despite evidence from Western studies linking family functioning to individual health. Using data from 1,190 respondents collected during the Moscow Health Survey 2004 we examined the association between family relations and health outcomes. Poorer family functioning was strongly associated with worse self-rated physical health and mental health. Our results suggest that the proximal social environment of the family is important for understanding health outcomes in contemporary Russia.

National Category
Sociology
Research subject
Baltic and East European studies
Identifiers
urn:nbn:se:sh:diva-29161 (URN)10.1080/09668136.2015.1100370 (DOI)000367004900007 ()
Available from: 2016-01-15 Created: 2016-01-15 Last updated: 2017-06-30Bibliographically approved
Stickley, A., Koyanagi, A., Leinsalu, M., Ferlander, S., Sabawoon, W. & McKee, M. (2015). Loneliness and health in Eastern Europe: findings from Moscow, Russia. Public Health, 29(4), 403-410.
Open this publication in new window or tab >>Loneliness and health in Eastern Europe: findings from Moscow, Russia
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2015 (English)In: Public Health, ISSN 0033-3506, E-ISSN 1476-5616, Vol. 29, no 4, p. 403-410Article in journal (Refereed) Published
Abstract [en]

OBJECTIVES: To examine which factors are associated with feeling lonely in Moscow, Russia, and to determine whether loneliness is associated with worse health.

STUDY DESIGN: Cross-sectional study.

METHODS: Data from 1190 participants were drawn from the Moscow Health Survey. Logistic regression analysis was used to examine which factors were associated with feeling lonely and whether loneliness was linked to poor health.

RESULTS: Almost 10% of the participants reported that they often felt lonely. Divorced and widowed individuals were significantly more likely to feel lonely, while not living alone and having greater social support reduced the risk of loneliness. Participants who felt lonely were more likely to have poor self-rated health (odds ratio [OR]: 2.28; 95% confidence interval [CI]: 1.38-3.76), and have suffered from insomnia (OR: 2.43; CI: 1.56-3.77) and mental ill health (OR: 2.93; CI: 1.88-4.56).

CONCLUSIONS: Feeling lonely is linked to poorer health in Moscow. More research is now needed on loneliness and the way it affects health in Eastern Europe, so that appropriate interventions can be designed and implemented to reduce loneliness and its harmful impact on population well-being in this setting.

National Category
Sociology
Research subject
Baltic and East European studies
Identifiers
urn:nbn:se:sh:diva-26568 (URN)10.1016/j.puhe.2014.12.021 (DOI)000353186600016 ()25744109 (PubMedID)2-s2.0-84928215517 (Scopus ID)
Available from: 2015-03-12 Created: 2015-03-12 Last updated: 2017-07-10Bibliographically approved
Koyanagi, A. & Stickley, A. (2015). The association between psychosis and severe pain in community-dwelling adults: Findings from 44 low- and middle-income countries. Journal of Psychiatric Research, 69, 19-26.
Open this publication in new window or tab >>The association between psychosis and severe pain in community-dwelling adults: Findings from 44 low- and middle-income countries
2015 (English)In: Journal of Psychiatric Research, ISSN 0022-3956, E-ISSN 1879-1379, Vol. 69, p. 19-26Article in journal (Refereed) Published
Abstract [en]

Previous studies examining the association between schizophrenia and pain have produced mixed results and data on sub-threshold psychosis or psychotic symptoms and pain are scarce. This study assessed the association between psychosis and severe pain among community-dwelling adults in 44 low- and middle-income countries (LMICs) where no data exists.Data on 235,370 adults aged ≥18 years from the World Health Survey (WHS) 2002-2004 were analyzed. The presence of past 12-month psychotic symptoms was established using four questions from the Composite International Diagnostic Interview. Participants were categorized into four mutually exclusive groups based on whether they had at least one psychotic symptom and/or a lifetime psychosis or schizophrenia diagnosis. Multivariable logistic regression was used to estimate the association between psychosis and past 30-day severe pain. The prevalence of severe pain among those with 0, 1, 2, ≥3 psychotic symptoms was 8.7%, 16.7%, 21.8%, 30.5% respectively. Compared to those with no psychotic symptoms or diagnosis, the ORs (95%CIs) were: at least one symptom without diagnosis [2.17 (1.99-2.38)]; no symptom with diagnosis [2.33 (1.71-3.17)]; at least one symptom and diagnosis [4.27 (3.20-5.71)]. Associations were partly mediated by chronic physical conditions, anxiety, and depression. Despite some limitations such as the use of a single-item question to assess pain, the results of this study suggest that individuals with psychotic symptoms or a psychosis diagnosis should be systematically assessed for pain, and if necessary, receive treatment for pain and its underlying conditions. Future research on the effect of pain management on psychosis outcome is warranted.

Keyword
Low-income countries, Middle-income countries, Pain, Psychotic symptoms, Schizophrenia
National Category
Sociology
Identifiers
urn:nbn:se:sh:diva-28276 (URN)10.1016/j.jpsychires.2015.07.020 (DOI)000361927800004 ()26343590 (PubMedID)2-s2.0-84940850638 (Scopus ID)
Available from: 2015-09-17 Created: 2015-09-17 Last updated: 2017-07-03Bibliographically approved
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ORCID iD: ORCID iD iconorcid.org/0000-0002-9565-5004

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